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Clinical and Experimental Dental... Aug 2022This study was done to determine the timing of eruption of permanent teeth by sex and the number of permanent teeth erupted at different ages and to assess its...
OBJECTIVES
This study was done to determine the timing of eruption of permanent teeth by sex and the number of permanent teeth erupted at different ages and to assess its association with malocclusion.
MATERIAL AND METHODS
The sample for this study consisted of 633 healthy subjects (317 boys and 316 girls) aged between 5.0 and 15.0 years. The subjects were divided into subgroups considering an age interval of 1 year.
RESULTS
The mean eruption times were lower for girls compared with boys except for the maxillary and mandibular second premolars and second molars, which were found to erupt earlier in boys. All the permanent mandibular teeth, except the second premolars, tended to erupt earlier than their maxillary antagonists in both sexes. The sequence of eruption differs between girls and boys in the maxillary canine and maxillary second premolars. In Class III malocclusion, all the permanent mandibular teeth erupt earlier than their maxillary antagonists. In the entire sample, the correlation between the number of erupted teeth and age was strong (p < .05), but the differences between sexes were not significant.
CONCLUSIONS
It is important to know the normal eruption time of permanent teeth in the population due to diagnosis and better treatment planning in pediatric dentistry and orthodontics.
Topics: Age Factors; Cuspid; Dentition, Permanent; Female; Humans; Male; Malocclusion; Tooth Eruption
PubMed: 35157778
DOI: 10.1002/cre2.544 -
Anales de Pediatria Jun 2021To assess whether the order of permanent tooth eruption may be a useful indicator of motor function laterality.
OBJECTIVES
To assess whether the order of permanent tooth eruption may be a useful indicator of motor function laterality.
METHODS
We conducted a cross-sectional study in schoolchildren aged 6-8 years old evaluated in the annual school-based routine dental health examinations conducted by the staff of the primary care centre of an urban district in Barcelona, Spain. We also evaluated hand, foot, eye, and auditory lateralities using a battery of simple exercises. Bivariate and multivariate analysis of data was performed.
RESULTS
The study sample included 388 children, 51.3% female, with a mean age of 6.5 years. Right laterality was the predominant side in every variable under study, especially in tooth eruption (310 children; 80%), handedness (349; 89.9%), and footedness (337; 86.8%). In the bivariate analysis, we found a statistically significant association of tooth eruption laterality with handedness and footedness, and of tooth eruption laterality with ocular and auditory lateralities (p<.001). In the multivariate analysis, tooth eruption laterality and foot laterality were independent variables significantly associated with hand laterality. The diagnostic accuracy of tooth eruption laterality and foot laterality in relation to hand laterality as reference, showed a similar sensitivity and positive and negative predictive values, but the specificity of dentition laterality was higher (79% versus 66%).
CONCLUSIONS
Laterality in the order of dental eruption is a useful indicator of right or left motor function laterality in developing individuals that may be particularly helpful to determine the main dominance in cases of crossed laterality.
Topics: Child; Cross-Sectional Studies; Dentition, Permanent; Female; Functional Laterality; Humans; Male; Spain; Tooth Eruption
PubMed: 34090636
DOI: 10.1016/j.anpede.2020.12.004 -
International Journal of Environmental... Mar 2022This prospective study examined a population of 520 urban and rural children aged 5 to 9 years. Every 2−4 weeks, the clinical symptoms accompanying primary tooth...
This prospective study examined a population of 520 urban and rural children aged 5 to 9 years. Every 2−4 weeks, the clinical symptoms accompanying primary tooth replacement such as a cough, a runny nose, pain, and body temperature were assessed in each child’s medical records. The authors were able to show in a statistically significant manner that the frequency, time, and type of cough were strongly related to the type of erupting teeth (p < 0.001 for each relationship). A cough dependent on the type of erupting teeth was observed in 86% to 92% of the examined children, with a morning bronchial cough being connected with an eruption of the lower teeth, and an eruption of the upper teeth producing an all-day pharyngeal cough caused by mucus secretions dripping down the back of the throat. A statistically significant relationship was also confirmed between the type of erupting teeth and the incidence of a runny nose (p < 0.001), the frequency of a runny nose (p < 0.001), and the time when runny nose symptoms occurred (p < 0.001). This study shows that the period when primary dentition is replaced with permanent teeth in children is characterized by a physiological cough and a runny nose.
Topics: Child; Cough; Dentition, Permanent; Humans; Prospective Studies; Tooth; Tooth Eruption
PubMed: 35328989
DOI: 10.3390/ijerph19063301 -
Wiadomosci Lekarskie (Warsaw, Poland :... 2021The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption.
OBJECTIVE
The aim: The paper was aimed at the study of the processes of mineralization of the enamel of the permanent tooth after its eruption.
PATIENTS AND METHODS
Materials and methods: To study the structure of the enamel of permanent teeth has been carried out using light and electron microscopy. The study of the process of the development of the primordia of the permanent teeth involved 10 culled puppies of 30-40 days of age. Microscopic, electron microscopic, immunohistochemical methods of research have been used to study the processes of histogenesis.
RESULTS
Results: The studies show that in the postnatal period, the formation of the crown, externally covered with cuticular epithelium, marks the formation of the primordium of the permanent tooth at the follicle stage. After eruption of a tooth, different parts of its crown have three individual structural and functional barriers to enamel biomineralization. The first one is provided by the cuticular epithelium of the pitted areas of the crown, which ensures filtering of the salivary fluid from the protein deposit in the form of a pellicle. The second barrier is defined on the lateral and cuspidate surfaces of the enamel, where the cuticle is erased or poorly expressed. The third structural and functional barrier of enamel biomineralization is located in the cervical portion of teeth of different classes.
CONCLUSION
Conclusions: Different areas of the enamel in the tooth crown have specific filtration barriers, which can be distinguished as follows: pit-and-fissure-and-groove, cuspidateand-approximal, and cervical barriers. The cuticle is poorly expressed or totally absent on the cusps of the tooth crowns in contrast to pitted areas.
Topics: Animals; Crowns; Dental Enamel; Dogs; Microscopy, Electron; Tooth; Tooth Eruption
PubMed: 34159907
DOI: No ID Found -
Acta Medica (Hradec Kralove) 2019The aim of this research is to study the effect of body overweight at birth (fetal macrosomia) on the processes of tooth eruption and tooth growth during the first year...
The aim of this research is to study the effect of body overweight at birth (fetal macrosomia) on the processes of tooth eruption and tooth growth during the first year of life in children in the Kharkiv City (Ukraine) population. One of the research tasks is to examine the features of deciduous teeth eruption in children who were born with macrosomia with different values of the weight-height index at birth. Materials and methods. The medical records of the children born between 1977 and 2013 have been analyzed. The database has been collected in one of the Kharkiv City clinic. The Main Group is comprised of the medical records of the children (separately for boys and girls) born with fetal macrosomia. All the medical records of the Main Group have been divided into subgroups taking into account the gender and the harmonious (well-balanced) development coefficient. The Comparison Group is comprised of the medical records of the children also born within the normal term range, but with weight and height that correspond to the gestation age (fetal normosomia). To determine the average time of the first tooth eruption, as well as the deciduous teeth growth rate for each of the groups under the study, we have used the hypothesis about a linear dependence between the number of erupted teeth and the age of the child. The statistical data processing and verification of the consistency of this hypothesis is performed using the multiple linear regression analysis with the STATISTICA 6.0 software package (Multiple Regression module). The number of delayed eruption and premature eruption cases observed is calculated along with the corresponding confidence intervals for the significance level, p, of less than 0.05, taking into account the binomial distribution of the random variable. The results of the study indicate a slowed growth rate of deciduous teeth in children born with macrosomia, as well as an increased number of cases (by a factor of 2 to 4 times) of deviations in the timing of teeth eruption compared to regional norms. The smallest growth rate of deciduous teeth and the smallest number of teeth at the age of one year are registered in macrosomic boys and macrosomic girls with a long body and a relatively reduced birth weight, as well as in macrosomic girls with intrauterine obesity. The macrosomic girls with intrauterine acceleration with obesity at the background have the largest average tooth growth rate and the largest percentage of premature eruption cases among all subgroups. Conclusions. The somatometric features of fetal macrosomia suggest the influence on the number of teeth that erupt by a certain age. The data on the deviation from the generally accepted terms of teeth eruption in children born with macrosomia, can be the basis for developing new and improving existing prevention programs aimed at preserving dental health.
Topics: Birth Weight; Body Height; Female; Fetal Macrosomia; Humans; Infant; Infant, Newborn; Male; Retrospective Studies; Tooth Eruption; Tooth, Deciduous; Ukraine
PubMed: 31184300
DOI: 10.14712/18059694.2019.48 -
Indian Journal of Dental Research :... 2020The aim of this study was to find a correlation between the permanent maxillary canine eruption and the cervical vertebral maturation index (CVMI).
AIM
The aim of this study was to find a correlation between the permanent maxillary canine eruption and the cervical vertebral maturation index (CVMI).
MATERIALS AND METHODS
145 subjects (73 male and 72 female) in the age of 7-14 years were examined radiographically with lateral cephalographs and orthopantomographs. The CVM patterns were evaluated on the lateral cephalograph using the classification of Hassel and Farman. The stage of the permanent maxillary canine eruption has been investigated on the orthopantomographs depending on its vertical height in relation to the adjacent incisor. Descriptive statistics were obtained for both CVMI stages and canine eruption grading. Spearman rank correlation test was used to determine the correlation between both methods. The minimum level of significance was considered less than 0.05 (P < 0.05).
RESULTS
Results showed a strong correlation between CVMI and the grading of the maxillary canine eruption in both female and male and the (r) value estimated was 0.862 and 0.758, respectively. Over 90% of deceleration stage of CVMI in both genders show canine eruption (pubertal growth spurt) about 91.66% for female and 95.65% for male and a small percentage of delay eruption 8.33% and 4.35% in female and male gender, respectively, with a predilection to the female gender.
CONCLUSIONS
A significant correlation between the permanent maxillary canine eruption stages and skeletal maturity was found. The eruption of maxillary canine occurs before the end of pubertal growth. Any delay in the eruption of maxillary canine after the deceleration stage of CVMI, suggesting a chance of impaction.
Topics: Age Determination by Skeleton; Cephalometry; Cuspid; Female; Male; Maxilla; Radiography, Panoramic; Tooth Eruption
PubMed: 32769275
DOI: 10.4103/ijdr.IJDR_29_19 -
BMC Oral Health Jul 2023The purpose of the study was to determine the possible relationship between the eruption of primary and permanent teeth and neonatal factors in German children according...
BACKGROUND
The purpose of the study was to determine the possible relationship between the eruption of primary and permanent teeth and neonatal factors in German children according to gender.
METHODS
A cross-sectional survey study was performed in 10 German orthodontic practices. Using a questionnaire information about gender, time of birth (week of pregnancy), birth weight (g) and height (cm), and the age of first primary and first permanent tooth eruption (months/years) of 405 children (230 girls and 175 boys) were collected. A Mann-Whitney U-test was used for group comparisons, and correlations were verified using a Pearson test.
RESULTS
No correlation was found between neonatal factors (time of birth, birth weight, and birth height) and primary tooth eruption for male participants. However, for females a low correlation was found between the eruption of the first primary tooth and birth weight (r = -0.18, CI: -0.30 to -0.042, p = 0.011) and birth height (r = -0.19, CI: -0.32 to -0.054, p = 0.006). No correlations between neonatal factors and the eruption of the first permanent tooth were found for either gender. A moderate correlation was found between the first primary and first permanent tooth eruption (females: r = 0.30, CI: 0.16 to 0.43, p < 0.001; males: r = 0.22, CI: 0.059 to 0.35, p = 0.008).
CONCLUSIONS
An earlier eruption of the primary teeth can be assumed with greater body weight and height at the time of birth for girls. For boys, the tendency is the opposite. However, there seems to be a catch-up growth effect due to the missing differences between both permanent tooth eruption times. Nevertheless, the first primary and the first permanent tooth eruption correlates in a German children population.
Topics: Child; Female; Infant, Newborn; Pregnancy; Humans; Male; Tooth Eruption; Birth Weight; Cross-Sectional Studies; Parturition; Statistics, Nonparametric
PubMed: 37393261
DOI: 10.1186/s12903-023-03153-1 -
Journal of Dental Research Jul 2021The aims of this study were to 1) determine if continuous eruption occurs in the maxillary teeth, 2) assess the magnitude of the continuous eruption, and 3) evaluate the...
The aims of this study were to 1) determine if continuous eruption occurs in the maxillary teeth, 2) assess the magnitude of the continuous eruption, and 3) evaluate the effects of continuous eruption on the different periodontal parameters by using data from the population-based cohort of the Study of Health in Pomerania (SHIP). The jaw casts of 140 participants from the baseline (SHIP-0) and 16-y follow-up (SHIP-3) were digitized as 3-dimensional models. Robust reference points were set to match the tooth eruption stage at SHIP-0 and SHIP-3. Reference points were set on the occlusal surface of the contralateral premolar and molar teeth, the palatal fossa of an incisor, and the rugae of the hard palate. Reference points were combined to represent 3 virtual occlusal planes. Continuous eruption was measured as the mean height difference between the 3 planes and rugae fix points at SHIP-0 and SHIP-3. Probing depth, clinical attachment levels, gingiva above the cementoenamel junction (gingival height), and number of missing teeth were clinically assessed in the maxilla. Changes in periodontal variables were regressed onto changes in continuous eruption after adjustment for age, sex, number of filled teeth, and education or tooth wear. Continuous tooth eruption >1 mm over the 16 y was found in 4 of 140 adults and averaged to 0.33 mm, equaling 0.021 mm/y. In the total sample, an increase in continuous eruption was significantly associated with decreases in mean gingival height ( = -0.34; 95% CI, -0.65 to -0.03). In a subsample of participants without tooth loss, continuous eruption was negatively associated with PD. This study confirmed that continuous eruption is clearly detectable and may contribute to lower gingival heights in the maxilla.
Topics: Adult; Dental Occlusion; Follow-Up Studies; Humans; Incisor; Maxilla; Tooth Eruption
PubMed: 33655796
DOI: 10.1177/0022034521999363 -
Matrix Biology : Journal of the... 2016Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a transmembrane zinc-endopeptidase that breaks down extracellular matrix components, including several collagens,...
Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a transmembrane zinc-endopeptidase that breaks down extracellular matrix components, including several collagens, during tissue development and physiological remodeling. MT1-MMP-deficient mice (MT1-MMP(-/-)) feature severe defects in connective tissues, such as impaired growth, osteopenia, fibrosis, and conspicuous loss of molar tooth eruption and root formation. In order to define the functions of MT1-MMP during root formation and tooth eruption, we analyzed the development of teeth and surrounding tissues in the absence of MT1-MMP. In situ hybridization showed that MT1-MMP was widely expressed in cells associated with teeth and surrounding connective tissues during development. Multiple defects in dentoalveolar tissues were associated with loss of MT1-MMP. Root formation was inhibited by defective structure and function of Hertwig's epithelial root sheath (HERS). However, no defect was found in creation of the eruption pathway, suggesting that tooth eruption was hampered by lack of alveolar bone modeling/remodeling coincident with reduced periodontal ligament (PDL) formation and integration with the alveolar bone. Additionally, we identified a significant defect in dentin formation and mineralization associated with the loss of MT1-MMP. To segregate these multiple defects and trace their cellular origin, conditional ablation of MT1-MMP was performed in epithelia and mesenchyme. Mice featuring selective loss of MT1-MMP activity in the epithelium were indistinguishable from wild type mice, and importantly, featured a normal HERS structure and molar eruption. In contrast, selective knock-out of MT1-MMP in Osterix-expressing mesenchymal cells, including osteoblasts and odontoblasts, recapitulated major defects from the global knock-out including altered HERS structure, short roots, defective dentin formation and mineralization, and reduced alveolar bone formation, although molars were able to erupt. These data indicate that MT1-MMP activity in the dental mesenchyme, and not in epithelial-derived HERS, is essential for proper tooth root formation and eruption. In summary, our studies point to an indispensable role for MT1-MMP-mediated matrix remodeling in tooth eruption through effects on bone formation, soft tissue remodeling and organization of the follicle/PDL region.
Topics: Animals; Dentinogenesis; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Matrix Metalloproteinase 14; Mesoderm; Mice; Mutation; Tissue Distribution; Tooth Eruption; Tooth Root
PubMed: 26780723
DOI: 10.1016/j.matbio.2016.01.002 -
Bone May 2024Osteogenesis imperfecta (OI) is a congenital disease comprising a heterogeneous group of inherited connective tissue disorders. The main treatment in children is...
INTRODUCTION
Osteogenesis imperfecta (OI) is a congenital disease comprising a heterogeneous group of inherited connective tissue disorders. The main treatment in children is bisphosphonate therapy. Previous animal studies have shown that bisphosphonates delay tooth eruption. The aim of this study is to determine whether patients with OI treated with pamidronate and/or zoledronic acid have a delayed eruption age compared to a control group of healthy children.
METHODS
An ambispective longitudinal cohort study evaluating the age of eruption of the first stage mixed dentition in a group of children with OI (n = 37) all treated with intravenous bisphosphonates compared with a group of healthy children (n = 89). Within the study group, the correlation (Pearson correlation test) between the type of medication administered (pamidronate and/or zoledronic acid) and the chronology of tooth eruption is established, as well as the relationship between the amount of cumulative dose received and tooth eruption.
RESULTS
The age of eruption of the study group was significantly delayed compared to the age of eruption of the control group for molars and lateral incisors (p < 0.05). Patients who received higher cumulative doses had a delayed eruption age compared to those with lower cumulative doses (p < 0.05). There is a high positive correlation between age of delayed tooth eruption and Zoledronic acid administration.
CONCLUSION
Patients with OI have a delayed eruption of the 1st stage mixed dentition compared to a control group of healthy children. This delayed eruption is directly related to the cumulative dose of bisphosphonates and the administration of zoledronic ac.
Topics: Child; Animals; Humans; Pamidronate; Zoledronic Acid; Osteogenesis Imperfecta; Tooth Eruption; Bone Density Conservation Agents; Longitudinal Studies; Diphosphonates; Bone Density
PubMed: 38458305
DOI: 10.1016/j.bone.2024.117069